Press release -
Novel Pharmacological Therapies for Coeliac Disease: A Presentation You Shouldn’t Miss
If you or someone you know is affected by coeliac disease, you may find maintaining a gluten-free diet challenging - or perhaps you still experience symptoms despite strict adherence. You are not alone. Up to 30% of patients continue to struggle with symptoms even while following a gluten-free diet.
Coeliac patients and professionals with expertise in the disease shouldn’t miss this insightful presentation by Professor Detlef Schuppan, a leading expert in the field.
In this recorded talk, he explores cutting-edge pharmacological therapies for coeliac disease, offering a comprehensive overview of novel treatment approaches that could transform disease management for those who continue to suffer despite dietary restrictions.
Understanding Coeliac Disease and Emerging Therapies
Coeliac disease is a common autoimmune condition triggered by gluten ingestion, affecting approximately 1.4% of the global population. While a strict gluten-free diet is currently the only treatment, it can be difficult to maintain and may not fully resolve symptoms for everyone.
Recorded at the AOECS Annual Conference in Madrid on November 15, 2024, Professor Schuppan’s presentation covers:
- The challenges of maintaining a gluten-free diet in today’s world and other factors beyond gluten that may influence coeliac disease.
- The latest pharmacological advancements, including glutinases, tight junction stabilisers, nanoparticulate tolerance, DQ2/DQ8 inhibitors, and transglutaminase inhibitors.
- Insights into a promising transglutaminase inhibitor that targets the central pathomechanism of coeliac disease.
- The future potential of these therapies for non-responsive coeliac disease and related conditions.
About Professor Detlef Schuppan
Professor Detlef Schuppan is a distinguished physician and scientist specialising in gastroenterology, immunology, and hepatology. He is widely recognised for his groundbreaking research on coeliac disease, gluten sensitivity, and fibrotic diseases. His work has significantly advanced our understanding of the disease, including identifying tissue transglutaminase (tTG) as the primary autoantigen in coeliac disease.
About the AOECS Annual Conference
The AOECS Annual Conference is a yearly key event organised by the Association of European Coeliac Societies (AOECS). It brings together national coeliac societies, researchers, policymakers, and industry representatives to discuss the latest developments in coeliac disease research, gluten-free food safety, and advocacy efforts. The next AOECS Annual Conference will be held on October 17, 2025, in Brussels, Belgium.
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The Association of European Coeliac Societies (AOECS) is an independent, non-profit umbrella organisation of over 40 member and affiliated National Coeliac Societies. Together with our members, we represent people affected by coeliac disease or dermatitis herpetiformis across Europe and beyond.
We are involved in several international initiatives to raise awareness of coeliac disease, gluten free diets, and encourage research into coeliac disease early diagnosis, patient’s quality of life and cure.
