Controlling the amount of heparan sulphate – a carbohydrate needed for foetal development
Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases. All new molecular knowledge concerning these chains is therefore important. Researchers can now show that the same enzyme which determines the charge pattern of the chains also determines their length.
Forensic DNA analysis checks the origin of cultured cells
Cell lines are cultured cells that are commonly used in medical research. New results from Uppsala University show that such cells are not always what they are assumed to be. Using genetic analyses, the researchers showed that a commonly used cell line which was established in Uppsala almost fifty years ago does not originate from the patient it is claimed to stem from.
Memory activation before exposure reduces life-long fear of spiders
Many people suffer from anxiety and fears, and a common treatment for these problems is exposure therapy. In a new study published in Current Biology, researchers at Uppsala University have shown how the effect of exposure therapy can be improved by disrupting the recreation of fear-memories in people with arachnophobia.
New study provides important insight into how tumours metastasise
Research has shown that the growth of cancerous tumours is affected by the transforming growth factor beta (TGF-beta) in the body’s cells; TGF-beta both suppresses and stimulates tumour development, but it has not been understood how this happens. A new study published in the journal Science Signaling today reveals important details behind this process.
Kevin Anderson is the new Zennström visiting Professor in Climate Change Leadership
Climate researcher Kevin Anderson will be Uppsala University’s second holder of the Zennström visiting professorship in Climate Change Leadership. He will continue the work of Doreen Stabinsky in establishing an environment that will be unique, both in Sweden and in the world.
Polyunsaturated fat in adipose tissue linked to lower mortality
In a study from Uppsala University, published in the American journal JAMA Cardiology, the fatty acid linoleic acid (Omega 6) in subcutaneous adipose tissue was linked to lower mortality among older men followed over a 15-year period.
Plenty of light during daytime reduces the effect of blue light screens on night sleep
The use of smartphones and tablet computers during evening hours has previously been associated with sleep disturbances in humans. A new study from Uppsala University now shows that daytime light exposure may be a promising means to combat sleep disturbances associated with evening use of electronic devices. The findings are published in the scientific journal Sleep Medicine.
Simplified approach to drug development with Upsalite
For the first time, researchers have revealed the nanostructure of the mesoporous magnesium carbonate Upsalite® and pore size control was achieved without organic templates or swelling agents. By controlling the pore structure of the material the amorphous phase stabilisation exerted on poorly soluble drug compounds can be tuned and the drug delivery rate can be tailored.
Magma-limestone interaction can trigger explosive volcanic eruptions and affect the global carbon cycle
In a new study researchers from Sweden and Italy show what happens when magma meets limestone on its way up to the surface. Magma-limestone interaction might help explain why volcanoes like Vesuvius in Italy and Merapi in Indonesia are particularly explosive and, moreover, it helps us to understand another source of natural carbon released to the atmosphere by volcanoes.
Antidepressants boost cognitive behavioural therapy for social anxiety
Treatments for social anxiety disorder often include either selective serotonin reuptake inhibitors (SSRIs) or cognitive behavioural therapy (CBT), but new research from Uppsala University indicates that social anxiety disorder is best treated with the combination of SSRI and CBT, which also improves emotion processing in the brain. The results are published in the British Journal of Psychiatry.