Uppsala University scientists have designed a new mouse model that facilitates study of factors contributing to the progression of human bladder cancer and of immune-system activation when the tumour is growing. Using this model, they have been able to study how proteins change before, while and after a tumour develops in the bladder wall. The study has now been published in PLOS ONE.
Researchers at Uppsala University have discovered lymph node-like structures close to the tumour in brain cancer patients, where immune cells can be activated to attack the tumour. They also found that immunotherapy enhanced the formation of these structures in a mouse model. This discovery suggests new opportunities to regulate the anti-tumour response of the immune system.
The tiny beetle Triamyxa coprolithica is the first-ever insect to be described from fossil faeces. The animal the researchers have to thank for the excellent preservation was probably the dinosaur ancestor Silesaurus opolensis, which 230 million years ago ingested the small beetle in large numbers.
A few males are enough to fertilise all the females. The number of males therefore has little bearing on a population’s growth. However, they are important for purging bad mutations from the population. This is shown by a new Uppsala University study providing in-depth knowledge of the possible long-term genetic consequences of sexual selection. The results are published in Evolution Letters.
Indonesia’s volcanoes are among the world’s most dangerous. Why? Through chemical analyses of tiny minerals in lava from Bali and Java, researchers from Uppsala University and elsewhere have found new clues. They now understand better how the Earth’s mantle is composed in that particular region and how the magma changes before an eruption. The study is published in Nature Communications.
New data from Uppsala Conflict Data Program (UCDP), at Uppsala University, show that the total number of fatalities stemming from organised violence increased in 2020, after five consecutive years of falling numbers. Despite a substantial decrease in violence in the two biggest wars of the 2010s, Afghanistan and Syria, UCDP registered more than 80,100 deaths in organised violence in 2020.
The Swedish Government was able to undertake and justify Swedish military involvement in Afghanistan 2002–2014 by describing it as a traditional Swedish contribution while differentiating it from American military operations in the region. Both consensus and a sense of continuity in foreign policy formulation are required to achieve broad support, finds a new dissertation from Uppsala University.
Swedish researchers from institutions including Uppsala University have spent four years gathering data from the areas affected by the major forest fire of 2014. In their study of how the ecosystem as a whole has been altered, they could see that water quality in watercourses quickly returned to normal, while forested areas continued to lose carbon for many years after the fire.
Uppsala University has appointed Cecilia Wikström to chair the governing board of the University’s new knowledge centre for nuclear disarmament and Professor Erik Melander to be the centre’s director. Following these appointments, the Alva Myrdal Centre can start its activities.
The chemical bisphenol F can induce changes in a gene that is vital for neurological development. This discovery was made by researchers at the universities of Uppsala and Karlstad, Sweden. The mechanism could explain why exposure to this chemical during the fetal stage may be connected with a lower IQ at seven years of age – an association previously seen by the same research group.
Researchers have successfully sequenced the entire genome from the skull of Peştera Muierii 1, a woman who lived 35,000 years ago. Her high genetic diversity shows that the out-of-Africa migration was not the great bottleneck in human development but rather this occurred during and after the most recent Ice Age. This new study, led by Professor Mattias Jakobsson, is published in Current Biology.
A same-sex marriage entered into in one EU Member State may not be recognised in another. The argument is often that such a marriage is too different from the country’s own laws and policies. In a new dissertation on private international law, Laima Vaige analyses how this application of the law compares with the European Convention on Human Rights and EU law.
Founded in 1477, Uppsala University is the oldest university in Sweden. With more than 50,000 students and 7,500 employees in Uppsala and Visby, we are a broad university with research in social sciences, humanities, technology, natural sciences, medicine and pharmacology. Our mission is to conduct education and research of the highest quality and relevance to society on a long-term basis. Uppsala University is regularly ranked among the world’s top universities.
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