New research study creates new opportunities for treating brain diseases
Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier. In a new study, a research group at Uppsala University describes their development of a new antibody design that increases brain uptake of antibodies almost 100-fold.
Increased cooperation between preschool and CHC to identify children with mental health problems
It is beneficial to systematise the exchange of information between parents, preschool and child care centres (CHCs) to increase the focus on young children with mental health problems. This is shown in a recently conducted study from Uppsala University, published in the journal PLOS One.
Inhibition of EZH2 might be new therapy of multiple myeloma
In a study published in the scientific journal Oncotarget, researchers from Uppsala University show how the protein EZH2 affects the development of multiple myeloma, and that inhibition of EZH2 could be used as a new strategy to treat the disease. The tumour form multiple myeloma is today incurable and it has been challenging to improve therapy.
Researchers discover ‘Marvel microbes’ explaining how cells became complex
In a new study published in Nature an international research group led from Uppsala University presents the discovery of a group of microbes that provide new insights as to how complex cellular life emerged. The study provides new details of how, billions of years ago, complex cell types that comprise plants, fungi, but also animals and humans, gradually evolved from simpler microbial ancestors.
Live cell imaging using a smartphone
A recent study from Uppsala University shows how smartphones can be used to make movies of living cells, without the need for expensive equipment. The study is published in the open access journal PLOS ONE, making it possible for laboratories around the world to do the same thing.
Studies of one of the world’s rarest birds, the Rufous-headed Robin
Researchers at the Chinese Academy of Sciences in Beijing and Uppsala University, Uppsala, Sweden have put together all known information about the endangered Rufous-headed Robin. Very few observations have been made since it was first discovered in 1905. The researchers suggest that its distribution might be larger than previously thought.
Therapy response in brain tumour cells is linked to disease prognosis
The brain tumour form glioblastoma is difficult to treat and has very poor prognosis. In a new study, published today in the journal Cell Reports, scientists from Uppsala University show that a type of stem cell in the tumour is present in different states, with different response to drugs and radiation. The results may open an avenue towards development of new treatment strategies.
Collective dynamics in magnetic nano-structures
Researchers at the Division of Solid-state Physics and the Division of Material Physics at Uppsala University have shown how the collective dynamics in a structure consisting of interacting magnetic nano-islands can be manipulated. Their findings are published in the scientific journal Scientific Reports
Localised immunotherapy new possibility to treat bladder cancer
Antibody-based immunotherapy is a new promising method to treat cancer. Unfortunately, today’s treatments can result in adverse side effects. New findings from Uppsala University show an alternative way to administer the therapy, which has the same effect on the tumour but less impact other parts of the body.
Endangered Australasian marsupials are ancient survivors of climate change
In a new paper, published in Scientific Reports, an international team of researchers has analysed fossils and DNA from living and recently extinct species to show that conservation sensitive Australasian marsupials are much older than previously thought.