Topics: Medicine
Brain biomarker in blood sample predicts stroke
Researchers at Uppsala University Hospital and Uppsala University have demonstrated that a simple blood test that reflects brain health can predict which people are most at risk of suffering a stroke. The discovery could contribute to more individualised treatment of patients with atrial fibrillation. The study has been published in the journal Circulation.
Genetic signatures provide prognostic information in colorectal cancer
Using a unique collection of genetic and clinical data for colorectal cancer, researchers at Uppsala University have revealed genetic new alterations and developed of a new molecular classifier of tumour variants. The finding could lead to improved possibilities for individualised therapies. This is shown in study recently published in the journal Nature.
New antibiotic class effective against multidrug-resistant bacteria
Scientists at Uppsala University have discovered a new class of antibiotics with potent activity against multi-drug resistant bacteria, and have shown that it cures bloodstream infections in mice. The new antibiotic class is described in an article in the scientific journal PNAS.
Lower survival rates for women than men with germ cell tumours
Women with a type of ovarian cancer known as germ cell tumours have a worse prognosis than men with similar tumours, i.e. testicular cancer. After five years with the disease, 98 percent of men were alive while the survival rate for women was only 85 percent. This has been revealed by a new study from Uppsala University and Uppsala University Hospital published in the Journal of Internal Medicine.
Important to involve both parents in breastfeeding
The most important support person for women to succeed in their ambition to breastfeed is the new mother’s partner. The partner also needs to be included through more support from healthcare professionals. For single mothers, alternative solutions must be found. “Single people are a vulnerable group and need other types of support," explains researcher Ingrid Blixt.
Many more infected by TBE virus than previously known
The number of infections by the tick-borne TBE virus that are not detected by health services is far higher than previously assumed. This has been shown in a new study of Swedish blood donors from Uppsala University and the University Hospital in Uppsala. The results have been published in the journal Eurosurveillance, which is associated with the EU’s Centre for Disease Prevention and Control.
New instrument for precision medicine in cardiovascular disease
Researchers at Uppsala University have developed an instrument that makes it possible to measure 21 biomarkers for cardiovascular disease simultaneously with great precision by means of a simple blood test. The aim is to use this type of tool to improve the prediction of cardiovascular complications and facilitate more personalised treatment for patients.
Some increase in cancer after 1986 Chernobyl disaster
The nuclear accident in Chernobyl in 1986 led to the spread of radioactivity across Sweden and Europe. In a long-term study now published in Environmental Epidemiology, researchers have used new, more specific calculation methods to show the connection between radiation dose and certain types of cancer.
Location of strong sense of discomfort in brain found
Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure in the brain that controls voluntary movements, may also play a role in the development of depression. The results could lead to better treatments for Parkinson's disease.
Genetics influence the risk of blood clots in oral contraceptive users
Women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills according to a new study from Uppsala University. The results have been published in the American Journal of Obstetrics and Gynaecology.
Contraceptive pills protect against rheumatoid arthritis
Contraceptive pills can reduce the risk of rheumatoid arthritis, while hormone treatment in connection with menopause can increase the risk later in life. In a new study of more than 200,000 women in the UK, researchers at Uppsala University have discovered connections between the use of sex hormones and the risk of developing rheumatoid arthritis.
Men with metastatic prostate cancer live longer thanks to new drugs
Survival rates for men with metastatic prostate cancer have increased by an average of six months, something which coincides with the gradual introduction of ‘dual treatment’ since 2016. This is according to a register study of all Swedish men diagnosed between 2008 and 2020. The results are published in the medical journal JAMA Network open.
New mechanism behind cancer cell growth revealed
Researchers from Uppsala University have revealed one of the mechanisms behind the growth of cancer cells in the blood cancer multiple myeloma. The study shows that the protein EZH2 interacts with a specific RNA molecule to block genes that are important for tumour growth. The findings might contribute to the development of new treatments for multiple myeloma patients.
Svante Pääbo named Alumnus of the Year 2023
He opened up a completely new field of research by sequencing the genome of our long-extinct relatives. For his scientific accomplishments, Svante Pääbo was awarded the Nobel Prize in Physiology or Medicine in 2022. He has now been named Uppsala University’s Alumnus of the Year 2023.
More mast cell progenitors during pollen season
The frequency of mast cell progenitors in the blood circulation is higher in asthma patients during the birch pollen season than outside of it. This has been demonstrated in a new study by Uppsala University, published in the scholarly journal Allergy.
New method to identify mutations in childhood brain tumors
Researchers at Uppsala university have developed a new method to find mutations in brain tumors in children. They could also show that the mutations identified by them changes how cancer cells respond to a cancer drug. These findings could lead to better diagnostics and more individualized treatment of children with brain tumors. The study is published in the journal PNAS.
Gut bacteria linked to fatty deposits in heart arteries
In a major Swedish study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques constitute a major cause of heart attacks. The study was led by researchers at Uppsala University and Lund University and the findings have now been published in the scientific journal Circulation.